What is CLEANMOOD®?

CLEANMOOD® is an Organic 5-HTP ingredient. As a result of it being a precursor to serotonin production in the brain, 5-HTP has been shown to support various important aspects of health such as healthy sleep, mood, stress and weight management.*

Why choose CLEANMOOD®?

Clean label

Organic

CLEANMOOD® is the only branded 5-HTP sourced from certified Organic Griffonia Simplicifolia Seeds*

Glyphosate Free

CLEANMOOD® is certified glyphosate free by The Detox Project

Water Extracted

CLEANMOOD® is a water soluble & water extracted

Plant-Based

CLEANMOOD® is a plant-based and vegetarian ingredient

Clinically Proven Benefits

A branded form of organic 5-HTP

  • 5-HTP is a precursor to the “feel-good” neurotransmitter, serotonin*
  • CLEANMOOD® at 150mg has been clinically proven to enhance mood and sleep quality in young adults 18-40 years old.**
  • CLEANMOOD® is shown to improve overall sleep quality**
  • CLEANMOOD® is shown to improve support sadness**
  • CLEANMOOD® is shown to improve support anxiousness**
  • CLEANMOOD® is shown to improve support stress**

Clinical Findings

CLEANMOOD® demonstrated a significant improvement in mood states of sadness, anxiousness, stress, and overall sleep quality compared to placebo when taken either as a supplement or functional food (bar).**

The efficacy and safety analysis exhibited that CLEANMOOD® taken twice daily for 25 days, was safe and effective in enhancing mood and sleep quality in young adults.**

* These statements have not been evaluated by the Food and Drug Administration. This product is not intended  to diagnose, treat, or prevent any disease.

**The data provided is preliminary and intended solely to support a forthcoming peer-reviewed publication within 2025. Findings may be subject to further analysis and are not final until the completion of the formal review process. Unauthorized use or distribution is prohibited.

Sustainable

CLEANMOOD® gives back to the community where the wild Griffonia Simplicifolia plants are harvested and maintained.

Versatile

CLEANMOOD® is offered in a versatile powder form that can be added to practically any application – with a shelf-life of two years, it has a neutral flavor, is water-soluble, and is heat and pH-stable.

Harvest Quality

We’re committed to keeping the environment as healthy as possible by abiding by certified organic practices and methods. That meant using clean water, clean soil, and zero pesticides throughout the planting, harvesting, and collecting process.

Frequently Asked Questions

What is CLEANMOOD®?

CLEANMOOD® is a certified organic 5-HTP ingredient sourced from Griffonia simplicifolia seeds. It is designed for functional wellness products that support healthy mood, relaxation, stress balance, and sleep quality. Available in a versatile powder form, CLEANMOOD® is suitable for use in dietary supplements, functional foods, and beverages.  

CLEANMOOD® delivers 5-HTP, a naturally occurring compound that serves as a direct precursor to serotonin production in the body. Serotonin is a key neurotransmitter involved in mood regulation, stress response, relaxation, and healthy sleep patterns. Because 5-HTP works directly within the serotonin pathway, CLEANMOOD® provides a clear, mechanism-based story for brands building products around mood, calm, and sleep.  

The clinically studied dose ofCLEANMOOD® is 150 mg of 5-HTP per day, administered in two divided doses. In the clinical study, this dose was taken twice daily for 25 days and demonstrated improvements in mood states including sadness, anxiousness, and stress, as well as overall sleep quality, compared to placebo. Reductions in salivary cortisol were also observed, providing a physiological marker consistent with the stress-support benefit.

CLEANMOOD® has a specific, well-understood mechanism. As a serotonin precursor, 5-HTP operates directly within a neurochemical pathway rather than providing broad, non-specific relaxation support. This gives brands a more targeted and substantiated positioning story. Beyond mechanism, CLEANMOOD® is differentiated by its organic certification, glyphosate-residue-free status, water extraction process, and non-GMO verification. It is also the only branded 5-HTP sourced from certified organic Griffonia simplicifolia, which adds a clean-label credential that most 5-HTP raw materials cannot match. 

Can CLEANMOOD® be used in food and beverage products?

Yes. CLEANMOOD® is formulated for versatility across multiple product formats. It is water-soluble, neutral in flavor, and positioned as heat and pH-stable, making it practical for use in dietary supplement capsules and powders, functional food products such as bars, powder beverage blends, and shots. For water-based ready-to-drink applications, brands should confirm finished-product stability, as extended aqueous storage can affect active 5-HTP retention over time. CLEANMOOD® has a stated shelf life of two years in its finished powder form. 

CLEANMOOD® is heat stable, pH stable, and water soluble with a neutral flavor profile, which supports its use across a wide range of product formats including bars, capsules, powders, and shots. These properties make it a practical choice for formulation across functional food and supplement categories. For ready-to-drink or water-based liquid applications, finished-product stability testing is recommended to confirm active 5-HTP retention under your specific storage and processing conditions.

Yes. 5-HTP has a well-established safety record in the published literature. It has been studied in clinical settings for decades across a range of populations and doses, with the most commonly noted considerations being GI sensitivity at higher doses and the importance of avoiding concurrent use with serotonergic medications. At the 150 mg daily dose supported by CLEANMOOD®‘s clinical data, 5-HTP is generally recognized as well tolerated in healthy adult populations. 

CLEANMOOD® is sourced from the seeds of Griffonia simplicifolia, a woody climbing shrub native to West and Central Africa and one of the richest natural plant sources of 5-HTP. The seeds are grown under certified organic practices with no synthetic pesticides, herbicides, or glyphosate, and 5-HTP is extracted using a water-based process that preserves the clean-label integrity of the finished ingredient.